The most serious Fosamax side effect is the development of a bone disease called osteonecrosis of the jaw(ONJ), or "dead jaw." Osteonecrosis of the jaw is a rare form of osteonecrosis affecting the maxillofacial region of the body.
The onset of ONJ is linked with the temporary or permanent loss of blood to bone tissue, leading to death of the tissue and the eventual collapse of the bone. There are approximately 10,000 to 20,000 new cases of osteonecrosis diagnosed each year in the United States, most of which occur as a result of some type of bone injury such as a fracture or dislocation.
In addition to being caused as a result of some type of trauma, instances of ONJ have also been caused as a result of using certain bisphosphonate drugs. Fosamax users run the risk of developing a serious case of osteonecrosis of the jaw and suffering through the extreme pain associated with the death of jawbone tissue. The pain associated with ONJ is said to be similar to that which is suffered when eyes are pulled out
Reminds me of my days working at the homeless shelter!
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